| Issue | #1 |
| Published | December 2001 |
| Cover Price | 7.50 USD |
| Pages | 116 |
| Editing | Brian Smith (Reprint); See individual stories for original editors |
| Notes | Cover numbering is #25-22. The figure in the foreground is placed over a collage of Marvel characters (Carlos Pacheco's Avengers, Alex Ross' Wolverine, Joe Quesada's Daredevil and Alan Davis' Fantastic Four) that are the background images for every cover in this series. |
| Characters | Spider-Man |
| Genre | superhero |
| Pencils | Mark Bagley |
| Inks | Mark Bagley (?) |
| Letters | Typeset |
| Notes | Cover numbering is #25-22. The figure in the foreground is placed over a collage of Marvel characters (Carlos Pacheco's Avengers, Alex Ross' Wolverine, Joe Quesada's Daredevil and Alan Davis' Fantastic Four) that are the background images for every cover in this series. |
| Characters | Wolverine; Kitty Pryde |
| Genre | superhero |
| Pencils | John Byrne |
| Inks | Terry Austin |
| Letters | Typeset |
| Editing | Louise Jones |
| Reprinted | From X-Men (Marvel, 1963 series) #141 (Jan. 1981) Cover |
| Genre | superhero |
| Script | Bob Greenberger |
| Letters | Typeset |
| Characters | FEATURE: X-Men--Professor X; Storm; Wolverine; Colossus; Angel; Nightcrawler; Kitty Pryde; GUESTS: Wolverine; Colossus; Storm; Sprite; Franklin Richards; and Magneto of 2013; Rachel Summers; Moira MacTaggert; Senator Robert Kelly; VILLAINS: Sentinels; New Brotherhood of Evil Mutants--Mystique; Destiny; Blob; Pyro; Avalanche; CAMEOS: Lois Lane; Jimmy Olsen |
| Synopsis | Rachel Summers sends Kitty Pryde back in time from 2013 to warn the X-Men that the new Brotherhood of Evil Mutants will try to kill Senator Kelly and begin a chain of events that spells doom for mutants. |
| Genre | superhero |
| Script | John Byrne (Co-Plot); Chris Claremont |
| Pencils | John Byrne |
| Inks | Terry Austin |
| Colors | Glynis Wein |
| Letters | Tom Orzechowski |
| Editing | Louise Jones |
| Reprinted | From X-Men (Marvel, 1963 series) #141 (Jan. 1981) |
| Characters | The Watcher; Mr. Fantastic; Invisible Girl; Human Torch; The Thing |
| Genre | superhero |
| Pencils | Jack Kirby |
| Inks | Joe Sinnott |
| Letters | Typeset |
| Editing | Stan Lee |
| Reprinted | From Fantastic Four (Marvel, 1961 series) #48 (March 1966) Cover |
| Genre | superhero |
| Script | Bob Greenberger |
| Letters | Typeset |
| Characters | FEATURE: Fantastic Four--Mr. Fantastic; Invisible Girl; Human Torch; The Thing; GUESTS: The Silver Surfer; The Watcher; Inhumans--Black Bolt; Karnak; Gorgon; Medusa; Crystal; VILLAINS: Galactus; Maximus; Seeker; Skrulls |
| Synopsis | The Silver Surfer arrives on earth and flags it for destruction by his world-eating boss, Galactus. |
| Genre | superhero |
| Script | Stan Lee |
| Pencils | Jack Kirby |
| Inks | Joe Sinnott |
| Letters | Artie Simek |
| Editing | Stan Lee |
| Reprinted | From Fantastic Four (Marvel, 1961 series) #48 (March 1966) |
| Characters | Spider-Man; Mr. Fantastic; Invisible Girl; Human Torch; The Thing |
| Genre | superhero |
| Pencils | Jack Kirby |
| Inks | Steve Ditko |
| Letters | Typeset |
| Editing | Stan Lee |
| Reprinted | From Amazing Spider-Man (Marvel, 1963 series) #1 (March 1963) Cover |
| Genre | superhero |
| Script | Bob Greenberger |
| Letters | Typeset |
| Characters | FEATURE: Spider-Man; GUESTS: Aunt May; J. Jonah Jameson; John Jameson |
| Synopsis | Newspaper publisher J. Jonah Jameson begins his legendary crusade against Spider-Man by touting his son John, an astronaut, as a true hero; Spidey ends up saving John's life in a rocket accident. |
| Genre | superhero |
| Script | Stan Lee |
| Pencils | Steve Ditko |
| Inks | Steve Ditko |
| Letters | John D'Agostino |
| Editing | Stan Lee |
| Reprinted | From Amazing Spider-Man (Marvel, 1963 series) #1 (March 1963) |
| Characters | FEATURE: Spider-Man; GUESTS: Fantastic Four--Mr. Fantastic; Invisible Girl; Human Torch; The Thing; VILLAIN: Chameleon |
| Synopsis | Spidey tangles with the F.F. and takes on the Chameleon. |
| Genre | superhero |
| Script | Stan Lee |
| Pencils | Steve Ditko |
| Inks | Steve Ditko |
| Letters | John Duffy |
| Editing | Stan Lee |
| Reprinted | From Amazing Spider-Man (Marvel, 1963 series) #1 (March 1963) |
| Characters | FEATURE: Spider-Man; GUESTS: Fantastic Four--Mr. Fantastic; Invisible Girl; Human Torch; The Thing |
| Synopsis | Spidey's webbing explained. |
| Genre | superhero |
| Script | Stan Lee |
| Pencils | Steve Ditko |
| Inks | Steve Ditko |
| Editing | Stan Lee |
| Reprinted | from Amazing Spider-Man Annual, The (Marvel, 1964 series) #1 |
| Characters | Daredevil; Elektra; Bullseye |
| Genre | superhero |
| Script | Bob Greenberger |
| Pencils | Frank Miller |
| Inks | Klaus Janson |
| Letters | Typeset |
| Editing | Denny O'Neil |
| Reprinted | From Daredevil (Marvel, 1964 series) #181 (April 1982) Cover in miniature |
| Characters | FEATURE: Daredevil; GUESTS: Elektra (Death); Foggy Nelson; Punisher; VILLAINS: Kingpin; Bullseye; Eric Slaughter; Turk; Grotto |
| Synopsis | Bullseye breaks out of prison; Elektra hunts down Foggy and is about to kill him until she recognizes him as Matt's buddy from college; Bullseye fights Elektra and kills her with her own sai; DD goes after Bullseye and ends up dropping him from a great height, breaking every bone in his body. |
| Genre | superhero |
| Script | Frank Miller |
| Pencils | Frank Miller (Breakdowns); Klaus Janson (Finishes) |
| Inks | Klaus Janson |
| Colors | Klaus Janson |
| Letters | Joe Rosen |
| Editing | Denny O'Neil |
| Notes | Story narrated by Bullseye. |
| Reprinted | From Daredevil (Marvel, 1964 series) #181 (April 1982) |
| Genre | superhero |
| Letters | Typeset |
| Notes | Countdown of the 100 greatest issues from #100-22. |
| Characters | Cyclops |
| Genre | superhero |
| Pencils | Salvador Larroca |
| Inks | Salvador Larroca (?) |
| Letters | Typeset |