| Issue | #577 |
| Published | May 2010 |
| Frequency | monthly |
| Cover Price | 2.99 USD |
| Pages | 36 |
| Editing | Tom Brevoort; Lauren Sankovitch (associate) |
| Characters | Fantastic Four [the Thing; Human Torch [Johnny Storm]; Mr. Fantastic; Invisible Woman]; Medusa; Black Bolt |
| Genre | super-hero |
| Script | Jonathan Hickman |
| Pencils | Alan Davis |
| Inks | Mark Farmer |
| Colors | Javier Rodriguez |
| Letters | typeset |
| Synopsis | An advertisement for Rexall Sundown's "Marvel Heroes" multivitamin and mineral supplement, featuring licensed Marvel characters. |
| Notes | inside front cover |
| Characters | Black Bolt; Medusa; Watcher; Fantastic Four [Mr. Fantastic; the Thing; Human Torch [Johnny Storm]; Invisible Woman]; the Summoner; Oola Udonta; Aladi Ko Eke; Onomi Whitemane; Avoe |
| Synopsis | The FF journey to the moon and learn that the Kree created subspecies of four other races in the same manner that they created the Inhumans and that those four races and the Inhumans are ready to come to earth to live. |
| Genre | super-hero |
| Script | Jonathan Hickman |
| Pencils | Dale Eaglesham |
| Colors | Paul Mounts |
| Letters | Rus Wooton [as VC's Rus Wooton] |
| Letters | typeset |
| Notes | This recap is between pages 2 and 3 of the Fantastic Four story. |
| Synopsis | An advertisement for Imperial Toys' "Oprtix 3-D Bubbles." |
| Notes | This advertisement is between pages 3 and 4 of the Fantastic Four story. |
| Synopsis | An advertisement for American Marketing Enterprises children's sleepwear, featuring licensed Marvel characters. |
| Notes | This advertisement is between page 6 of the Fantastic Four story and the "How to Train Your Dragon" advertisement. |
| Synopsis | An advertisement for Cressida Cowell's "How to Train Your Dragon" novels. |
| Notes | This advertisement is between the AME sleepwear advertisement and page 7 of the Fantastic Four story. |
| Synopsis | An advertisement for FAB Starpoint school supplies, featuring Iron Man. |
| Notes | This advertisement is between pages 9 and 10 of the Fantastic Four story. |
| Synopsis | An advertisement for Pager Magic Groups' "Marvel Heroes Stickerfitti" stickers. |
| Notes | This advertisement is on the upper half of the page between page 13 of the Fantastic Four story and the "Thor and the Warriors Four" promotional. |
| Synopsis | An in-house promotional advertisement for Thor and the Warrior Four (Marvel, 2010 series) #1. |
| Notes | This advertisement is on the lower half of the page between the "Stickerfitti" advertisement and page 14 of the Fantastic Four story. |
| Synopsis | An in-house promotional advertisement for Uncanny X-Men (Marvel, 1981 series) #523. |
| Notes | This advertisement is between page 20 of the Fantastic Four story and the Black Widow advertisement. |
| Synopsis | An in-house promotional advertisement for Black Widow: Deadly Origin (Marvel, 2010 series), Black Widow: Web of Intrigue (Marvel, 1999 series), and Black Widow: The Sting of the Widow (Marvel, 2010 series). |
| Notes | This advertisement is between the Uncanny X-Men promotional and page 21 of the Fantastic Four story. |
| Synopsis | Letters of comment from Mathias Lewis; Steve Oelrich; Jeff Coburn; Brian Edwards; and Jordan F. Cooper. |
| Script | Jonathan Hickman |
| Letters | typeset |
| Notes | This letters column follows the final page of the Fantastic Four story. |
| Synopsis | An advertisement for Dr. Fresh's "Firefly" children's toothbrushes, featuring Marvel and Mattel licensed characters. |
| Notes | inside back cover |
| Synopsis | An advertisement for Jackks Pacific's "Monsuno." |
| Notes | back cover |