| Issue | #21 |
| Published | November 2007 |
| Cover Price | 2.99 USD |
| Pages | 36 |
| Editing | Mark Doyle (Assistant Editor); Jonathan Vankin (Editor) |
| Genre | Horror; Satire |
| Pencils | Philip Bond |
| Inks | Philip Bond |
| Colors | Philip Bond |
| Synopsis | "The Mutated Mayan Hissers are somewhere in the bowels of L.A., ready to unleash their assault on our civilization. But the Exterminators discover that tracking an enemy with 3,000 years of practice hiding from humans is their most difficult out-call yet." From Previews |
| Genre | Horror; Satire |
| Script | Simon Oliver |
| Pencils | Darick Robertson |
| Inks | John Lucas |
| Colors | Brian Buccellato |
| Letters | Pat Brosseau |