| Issue | #22 |
| Published | October 2007 |
| Cover Price | 2.99 USD; 3.75 CAD |
| Pages | 44 |
| Editing | Andy Schmidt; Nick Lowe; Will Panzo (assistant) |
| Characters | M [Monet St. Croix]; Siryn [Theresa Rourke Cassidy] |
| Genre | Superhero |
| Pencils | Pablo Raimondi (signed) |
| Inks | Pablo Raimondi (signed) |
| Colors | Brian Reber (signed) |
| Letters | typeset |
| Notes | Production by Anthony Dial. |
| Characters | X-Factor [Multiple Man [Jamie Madrox]; M [Monet St. Croix]; Layla Miller; Rictor [Julio Esteban Richter]; Theresa Rourke Cassidy [Siryn]; Strong Guy [Guido Carosella]; Rahne Sinclair [Wolfsbane]]; Molly; Wally; Solo [James Bourne]; Clay; VILLAINS: Isolationist [Josef Huber]; Nicole |
| Synopsis | Meet Molly and Wally, two charming children who go around the country singing cheerful songs that incite people to violence against mutants. Siryn and Monet have been dispatched to deal with them...except the twins have a rather unexpected protector. Meanwhile the Isolationist continues his manipulations to establish a world where mutants need never live in fear again. Question is, by the time he's done... will they be living at all? [per solicitation] |
| Genre | Superhero |
| Script | Peter David |
| Pencils | Pablo Raimondi |
| Inks | Pablo Raimondi |
| Colors | Brian Reber |
| Letters | Cory Petit of Virtual Calligraphy [as VC's Cory Petit] |
| Genre | Superhero |
| Script | Peter David |
| Pencils | Pablo Raimondi |
| Inks | Pablo Raimondi |
| Colors | Brian Reber |
| Letters | typeset |
| Notes | Recap of story-to-date and creator credits. Pinup is from cover to X-FACTOR #21. Recap is between pages 3 and 4 of the main story. |
| Characters | Wolverine |
| Genre | Superhero |
| Letters | typeset |
| Notes | Recap of ENDANGERED SPECIES story-to-date. |
| Characters | Beast [Henry McCoy]; Dark Beast [Henry McCoy] |
| Synopsis | Dark Beast shares his memories with Hank McCoy. |
| Genre | Superhero |
| Script | Mike Carey |
| Pencils | Mike Perkins |
| Inks | Andrew Hennessy |
| Colors | Raul Trevino |
| Letters | Joe Caramagna of Virtual Calligraphy [as VC's Joe Caramagna] |
| Notes | Story continued from UNCANNY X-MEN #489 and story continues in NEW X-MEN #41. |