| Issue | #21 |
| Published | July 2005 |
| Cover Price | $2.99 |
| Pages | 36 |
| Editing | Axel Alonso |
| Characters | Punisher |
| Genre | Crime |
| Pencils | Tim Bradstreet |
| Inks | Tim Bradstreet |
| Colors | Tim Bradstreet |
| Letters | Typeset |
| Characters | Punisher; O'Brien; Roth; Nicky Cavella |
| Synopsis | The Punisher goes on a rampage to get revenge against Nicky Cavella. O'Brien escapes from prison. |
| Genre | Crime |
| Script | Garth Ennis |
| Pencils | Leandro Fernandez |
| Inks | Scott Hanna |
| Colors | Dan Brown |
| Letters | Virtual Calligraphy's Randy Gentile |